Stars Vincent Price, Joseph Cotten, Hugh Griffith, Terry-Thomas and Virginia North. A fiery car crash results in the death of a Doctor Phibes (Vincent Price) and severe injuries to his wife. The woman doesn't survive surgery. The BIG news, is the doctor isn't really dead, just disfigured, with a skull-like face -- and he's completely insane. He blames the operating doctor's on the death of his wife. He goes about, systematically and creatively, killing them. Using the great plagues as a blueprint for murders, he sets about his new life's work.